Biological IF hypothesis

This may not make sense to most of you, but I am totally stoked. Scan for the important details. If you’re a biology person…what do you think?

Backstory: DH has spherocytosis. The lining of his red blood cells is too thin, so instead of being round it’s spherical. He has had his spleen removed so it doesn’t kill him. His mother, aunts, uncle, and sister all have it too. He also has morphology/motility issues.

I was in biology class today and we were discussing eukaryotic cells. Eukaryotic cells have a cytoskeleton that gives them shape and is also what causes them to be motile. (Anyone see where I’m going with this yet?!) Red blood cells, when they are created, are eukaryotic (although later they aren’t). So the DO have a cytoskeleton. Sperm are also eukaryotic and have a cytoskeleton.

Dh’s red blood cells are a funny shape. So is his sperm. He also only has about 51% motility. I am beginning to think that he has a cytoskeleton issue…causing both the blood disorder AND the infertility. His one uncle has spherocytosis and can’t have kids. They’ve always assumed it’s because he had the mumps as a kid. Maybe it’s not!!! MAYBE THE TWO ARE LINKED!

There is no cure for spherocytosis. It’s really rare. There is no cure for funky morphology either. I’m wondering…do the two share a chromosome or a protein? Could there be a cure for both, something no one has put together? I’m going to talk to my professor on Tuesday. Meanwhile…omg I’m thrilled at the idea. Even if there isn’t a “fix”, maybe there’s a reason!!!

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2 Comments

  1. Hey there

    I have been reading a few of your posts. I’m sorry that one of the ‘simple’ things in life has become such a struggle for you both. Trust me, I know how that feels.

    Also I do understand how you feel about your sisters.
    My sister is about to have number 3. Shes due in March and is already talking about number 4. anyone would think the girl was Catholic!!
    Most of the time I just wish she would stop so I can catch up!!

    Hugs Brenda
    xxx

    Reply
  2. I’m curious! – What did the prof say?

    Reply

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